I thought someone asked about the Crimson Trace interfering with holster carry but I can't find the thread so I started a new one. The pic shows how the laser comes close, but does not interfere with the gun seating properly in this Mitch Rosen Premier. The pic will give you an idea as to how other holsters may relate to the lasers placement on the grip.

This holster is available on the Kahr site and I highly recommend it for those who carry OWB.